Y Chromosome
XY
*
- is much
smaller than its homolog, the
X chromosome
- holds only a
dozen or so genes
(X holds 2,000 to 3,000 genes)
involved in male fertility (code for testes
proteins - many are repeat
amplified)
- holds some "housekeeping
genes" (†)
& genes with homology to the "X"
(‡)
fig*
- holds lots of "junk" DNA
& STR's (Short Tandem
Repeats)
- holds a gene -
SRY (sex determining region) encodes a protein that
triggers
formation of testes by activating genes on several of the autosomes.
X &
Y evolved from a matching pair of
autosomes some 240 to 320 millions years
ago
tips of
X & Y can engage in recombination, but rest of
Y
can not
the degeneration of Y chromosome
occurred after evolution of SRY gene, because
of a loss of ability to recombine
during meiosis... without recombination genes on
Y mutated, stopped working, &
degenerated
fig*
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